Relative vs. absolute risk
Many wellness services quote relative risk reductions — numbers that sound dramatic. A 40% relative reduction on a small absolute risk can mean very little for you personally. We translate both, always.
Our cardiovascular approach follows internationally recognised prevention guidelines, including European cardiology and lipidology recommendations.
We prioritise markers with substantial outcome evidence — apoB, Lp(a), HbA1c, blood pressure — over novelty tests.
Single values are weak evidence. We build decisions on trajectories measured under comparable conditions.
Where evidence is immature — microbiome analysis, for example — we say so, prominently.
We do not claim to extend life or guarantee health improvements. We provide measurement, interpretation and structured care.
Our editorial content is written to a standard you could take to your own physician.
Editorial
Many wellness services quote relative risk reductions — numbers that sound dramatic. A 40% relative reduction on a small absolute risk can mean very little for you personally. We translate both, always.
Observational data shows relationships; it cannot prove that changing X will change Y. We are explicit about which interventions rest on randomised evidence and which rest on reasonable inference.
Novel biomarkers are marketed long before they are validated. Our rule: a marker enters clinical use when guidelines or outcome studies support it — not when press coverage peaks.
Consumer wearables are useful for trends — sleep, activity, HRV. They are not diagnostic devices. We use them as continuous context around clinical measurements, never as a substitute.
A starting point for reading the evidence we build on.
Ference et al., “Low-density lipoproteins cause atherosclerotic cardiovascular disease”, European Heart Journal, 2017
The mechanistic and genetic case for apoB-containing lipoproteins as causal.
Emerging Risk Factors Collaboration, New England Journal of Medicine, 2009
Major individual-participant-data analysis of risk factors and vascular mortality.
ESC/EAS Guidelines for the management of dyslipidaemias
European Society of Cardiology and European Atherosclerosis Society recommendations.
Task Force of the European Society of Cardiology, “Heart rate variability: standards of measurement”, European Heart Journal, 1996
The foundational standards for HRV measurement and interpretation.
References are provided for context and do not constitute medical advice or endorsement of any specific outcome.

If you want to know why a marker is in (or out of) our panels, ask. We answer in writing.
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